Oncology Application Notes and Publications

Application notes or posters for download:

Optical Imaging of MMPSense as a Biomarker of Matrix Metalloprotease Activity In Vivo (2007) (4.4 MB)
Quantitative In vivo Fluorescence Imaging of Cancer Metastasis to the Lung and Response to Therapy (2007) (517.7 kB)
Accurate Quantification and Localization of Fluorescent Imaging Probes in vivo Using Fluorescent Molecular Tomographic Imaging (209.6 kB)
A New Platform of Superbright Fluorescent Nanoparticles for In Vivo Imaging (2006) (731.6 kB)
Non-Invasive optical imaging of lung metastasis and response to cancer therapy (2006) (147.5 kB)
In vivo tomographic and endoscopic imaging of experimental orthotopic colorectal cancer (2006) (197.8 kB)
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Publications

A spatially and temporally restricted mouse model of soft tissue sarcoma.
Kirsch D.G, Dinulescu D.M, Miller J.B, Grimm J, Santiago P.M, Young N.P, Nielsen G.P, Quade B.J, Chaber C.J, Schultz C.P, Takeuchi O, Bronson R.T, Crowley D, Korsmeyer S.J, Yoon S.S, Hornicek F.J, Weissleder R, Jacks T. Nature Medicine, Vol. 13 Issue 8, p992-997 (2007)
Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice.
Alencar H , Funovics MA , Figueiredo J, Sawaya H , Weissleder R , Mahmood U . Radiology. Jul;244(1):232-8. Epub May 16 (2007)
Selective antitumor effect of novel protease-mediated photodynamic agent.
Choi Y, Weissleder R, Tung CH. Cancer Res. Jul 15;66(14):7225-9 (2006)
Use of gene expression profiling to direct in vivo molecular imaging of lung cancer.
Grimm J , Kirsch DG , Windsor SD , Kim CF , Santiago PM , Ntziachristos V , Jacks T , Weissleder R . Proc Natl Acad Sci USA. 102(40):14404-9 (2005).
Use of gene expression profiling to direct in vivo molecular imaging of lung cancer
Proc Natl Acad Sci USA , October (2005)
Tomographic fluorescence mapping of tumor targets.
Montet et al., Cancer Research Jul 15, 65 (14):6330-6, (2005)
Detection of Dysplastic Intestinal Adenomas Using Enzyme-Sensing Molecular Beacons in Mice
Gastroenterology, February (2002)
In vivo imaging of tumors with protease activated near-infrared fluorescent probes.
Nature Biotechnology, April (1999)