ProSense- related publications

A spatially and temporally restricted mouse model of soft tissue sarcoma. Kirsch D.G, Dinulescu D.M, Miller J.B, Grimm J, Santiago P.M, Young N.P, Nielsen G.P, Quade B.J, Chaber C.J, Schultz C.P, Takeuchi O, Bronson R.T, Crowley D, Korsmeyer S.J, Yoon S.S, Hornicek F.J, Weissleder R, Jacks T. Nature Medicine, Vol. 13 Issue 8, p992-997 (2007)

Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice. Alencar H , Funovics MA , Figueiredo J, Sawaya H , Weissleder R , Mahmood U . Radiology. Jul;244(1):232-8. Epub May 16 (2007)

Selective antitumor effect of novel protease-mediated photodynamic agent. Choi Y, Weissleder R, Tung CH. Cancer Res. Jul 15;66(14):7225-9 (2006)

Use of gene expression profiling to direct in vivo molecular imaging of lung cancer. Grimm J , Kirsch DG , Windsor SD , Kim CF , Santiago PM , Ntziachristos V , Jacks T , Weissleder R . Proc Natl Acad Sci U S A. 102(40):14404-9 (2005).

Use of gene expression profiling to direct in vivo molecular imaging of lung cancer Proc Natl Acad Sci U S A , October (2005)

In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Wunder A , Tung CH , Muller-Ladner U , Weissleder R , Mahmood U . Arthritis & Rheumatism 50(8), 2459-2465 (2004).

In vivo imaging of proteolytic activity in atherosclerosis. Chen J, Tung CH , Mahmood U , Ntziachristos V , Gyurko R , Fishman MC , Huang PL , Weissleder R . Circulation 105(23), 2766-2771 (2002).

In vivo tomographic imaging of near-infrared fluorescent probes. Ntziachristos V , Bremer C , Graves EE , Ripoll J , Weissleder R . Molecular Imaging 1(2), 82-88 (2002).

In vivo Imaging of Proteolytic Activity in Atherosclerosis Circulation, June (2002)

Detection of Dysplastic Intestinal Adenomas Using Enzyme-Sensing Molecular Beacons in Mice Gastroenterology, February (2002)

Fluorescence molecular tomography resolves protease activity in vivo Nature Medicine, July (2002)

In vivo imaging of tumors with protease activated near-infrared fluorescent probes Nature Biotechnology, April (1999)

MMPSense - related publications

Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo. Deguchi JO , Aikawa M , Tung CH , Aikawa E , Kim DE , Ntziachristos V , Weissleder R , Libby P . Circulation 114(1):55-62 (2006).

Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL. Circulation 111(14), 1800-1805 (2005).

Fluorescence molecular tomography resolves protease activity in vivo Nature Medicine, July (2002)

In vivo molecular target assessment of matrix metalloproteinase inhibition. Bremer C , Tung CH , Weissleder R . Nature Medicine 7(6), 743-748 (2001)