Revealing more information than FRI

Matrix metalloproteinases activity in HT-29 tumors

Following therapeutic response

FMT System and ProSense
FMT System with ProSense
Protease activity in 4T1 breast cancer metastasis in the lung

Scanning for disseminated metastases – consistent with known histology

Analysis of femur and vertebral metastases using ProSense 750
Consistent pattern of tumor metastases in the femoral region
Consistent pattern of tumor metastases in spinal and pelvic bone region

Monitoring normal bone remodeling

Clear imaging of lumbar and sacral vertebrae using OsteoSense
Image: Coronal tomography slice at the depth of the vertebral column.
Investigation: Adult female Swiss Webster mouse injected with OsteoSense 750 and imaged 24 hours later using FMT system. Fluorescence signal within this spinal region was quantified as 35 pmols

Information to download:

Accurate Quantification and Localization of Fluorescent Imaging Probes In vivo Using Fluorescent Molecular Tomographic Imaging (204.6 kB)
FMT system information sheet (191.4 kB)
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