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In vivo imaging in small animal models

3D analysis and quantification of biological changes in deep tissue

Quantification in deep tissue
Ventral scan left tumor quantification: 304 pmol
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Ventral scan left tumor quantification: 304 pmol
Dorsal scan left tumor quantification: 314 pmol
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Dorsal scan left tumor quantification: 314 pmol
Ventral and dorsal scans of mouse with HT-29 tumor xenografts

High resolution in deep tissue
High resolution in deep tissue
Coronal FMT slice showing sub-millimeter resolution in solid-resin phantom. Total imaging time: Scan 2 – 4 min., Reconstruction 1 – 3 min.
Axial FMT slice of metastatic lung tumors using ProSense

3D analysis and quantification
3D analysis and quantification
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Quantitative data extracted by defining 3D regions of interest over which fluorescence can be analyzed
Quantification and distribution in user-specified regions of interest
Tomographic slicing
Exhibits strict linearity over a broad range of biologically relevant fluorochrome concentrations

Rapid, easy imaging
Scan times in the order of 2-4 minutes
Easy alignment, integrated index-matching fluid handling system, heated imaging chamber compatible with gas anesthesia
Fully automated software control of laser, camera, filter settings and fluid handling

Easy to use image acquisition and archiving software
Easy to use image acquisition and archiving software
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Single animal, simultaneous, direct injection of 680 and 750 fluorophores. Resulting images gated at same level
Dual channel imaging offering multiplexing at 680 nm and 750 nm
No channel cross-talk

Compatible with near-infrared fluorescence agents from VisEn and other suppliers
Please contact your local representative for information and pricing of VisEn systems.
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Product Order Code
FMT System
p.o.a.
Index Matching Fluid (FMT System only)
10094
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